Studies on induced oedema and arthritis and on human arthritis proved anti-inflammatory potency of the water extract of Guduchi. It also has antipyretic action and is a morphine potentiator. It induced reduction in blood sugar in alloxan induced hyperglycemic rats and rabbits. This drug relaxes the intestinal and uterine smooth muscles. Blood urea levels in uraemic dogs and human subjects were also decreased. It is proved effective in prevention of fibrosis and in stimulating regeneration in hepatic tissue.

Guduchi has been proven to be effective in inhibiting the growth of bacteria and enhancing the buildup of immune resistance. Scientific research is now providing clues to Guduchi's immune-boosting ability to fight diseases. In a study using human white blood cells, Guduchi increased the killing ability of macrophages, the immune cells responsible for fighting invaders.

The hypoglycaemic potential of Tinospora cordifolia has been studied, extensively. Administration of the aqueous extract to alloxan induced hyper- glycaemic rats and rabbits in a dose of 400 mg/kg body weight induced reduction in blood sugar. Reduction in blood sugar levels has been reported in adrenaline induced hyperglycaemia in rates, as also a favourable glucose tolerance in this rodent species on exposure to an aqueous extract of Tinospora cordifolia.

Tinospora cordifolia was also tested for its ability to modulate the changes occurring in the phagocytic activity of peritoneal macrophages after exposure of rats to either carbon tetrachloride or horse serum. It was found to normalize the phagocytic function irrespective to the direction of change, complying to the definition of an adaptogen.

The effect of Guduchi, an indigenous agent with proven hepatoprotective activity, was evaluated on Kupffer cell function, using carbon clearance test as a parameter.